The No. One Question That Everyone In ADHD Medication Pregnancy Needs To Know How To Answer
ADHD Medication During Pregnancy and Breastfeeding
The choice of whether to stop or continue ADHD medications during pregnancy and breastfeeding is challenging for women with the condition. There are few data on how exposure to ADHD for a long time could affect a fetus.
A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological problems like hearing loss or vision, febrile seizures, or IQ impairment. The authors acknowledge the need for higher-quality studies.
Risk/Benefit Analysis
Women who are pregnant and taking ADHD medications must weigh the advantages of taking them against the potential risks to the foetus. Doctors don't have the necessary data to provide clear recommendations but they can provide information on risks and benefits that assist pregnant women in making informed decisions.
A study published in Molecular Psychiatry concluded that women who took ADHD medication in early pregnancy were not at higher risk of fetal malformations or structural birth defects. Researchers used a vast population-based study of case-control to determine the prevalence of major structural birth defects in infants born to mothers who took stimulants during early pregnancy and those who had not. Clinical geneticists and pediatric cardiologists examined the cases to ensure correct case classification and to minimize the chance of bias.
The study of the researchers was not without limitations. The researchers were unable to, in the first place, to separate the effects caused by the medication from the disorder. That limitation makes it difficult to know whether the small differences observed in the exposed groups result from medication use or confounding by comorbidities. Additionally, the researchers did not study long-term offspring outcomes.
The study found that babies whose mothers had taken ADHD medication during pregnancy had a higher chance of being admitted to the neonatal care unit (NICU), compared to mothers who did not take any medication during pregnancy or had stopped taking their medication before or during pregnancy. This was due to central nervous system-related disorders and the increased risk of admission did not appear to be affected by the type of stimulant medication was used during pregnancy.
Women who took stimulant ADHD medication during pregnancy were also at an elevated risk of having a caesarean delivery or having a baby born with low Apgar score (less than 7). These risks did not appear to be influenced by the type of medication that was used during pregnancy.
The research suggests that the small risk associated with the use of ADHD medications during early pregnancy may be offset by the higher benefit for both mother and child from continued treatment for the woman's condition. Physicians should discuss the issue with their patients and, where they are able, assist them in developing strategies to improve their coping abilities which can reduce the impact of her disorder on her daily functioning and relationships.
Medication Interactions
As more women than ever are being diagnosed with ADHD and being treated with medication, the dilemma of whether or not to stop treatment during pregnancy is one that doctors are having to confront. These decisions are often made without clear and reliable evidence. Instead, physicians must consider their own expertise, the experience of other doctors, and the research on the topic.
The issue of possible risks to infants is extremely difficult. Many of the studies on this topic are based on observations rather than controlled research and their conclusions are often contradictory. Most studies restrict their analysis to live births, which may underestimate the teratogenic impact leading to abortions or terminations of pregnancy. The study discussed in the journal club addresses these issues, by examining both the data from deceased and live births.
The conclusion The conclusion: While some studies have found a positive association between ADHD medications and the risk of certain birth defects, other studies have found no connection and the majority of studies have a neutral or slight negative effect. Therefore an accurate risk-benefit analysis must be conducted in every case.
For women suffering from ADHD and ADD, the decision to stop medication is difficult if not impossible. In a recent article published in Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can cause depression and feelings of isolation. In addition, a decrease in medication can interfere with the ability to complete job-related tasks and drive safely that are crucial aspects of a normal life for many people with ADHD.
She suggests that women who are unsure whether to continue taking the medication or stop due to pregnancy educate family members, coworkers and friends about the condition, its effects on daily functioning, and the benefits of continuing the current treatment plan. It can also help women feel supported in her decision. It is also worth noting that certain drugs can pass through the placenta so if the patient decides to discontinue her ADHD medication during pregnancy and breastfeeding, she should be aware that traces of the medication could be transferred to the infant.
Risk of Birth Defects
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows, so do concerns over the impact that these drugs could have on fetuses. A recent study published in the journal Molecular Psychiatry adds to the existing knowledge about this subject. Researchers utilized two massive datasets to analyze more than 4.3 million pregnant women and determine whether stimulant medications increased birth defects. Researchers discovered that, while the risk overall is low, first-trimester ADHD exposure to medication was associated with slightly higher risk of certain heart defects, such as ventriculoseptal defect.
The researchers of the study didn't discover any link between early use of medication and other congenital anomalies such as facial deformities or club feet. The results are consistent with previous studies showing a small but significant increase in the risk of cardiac malformations in women who started taking ADHD medications prior to the time of pregnancy. This risk increased during the latter part of pregnancy when many women began to stop taking their medication.
Women who were taking ADHD medication during the first trimester were more likely need a caesarean, have an insufficient Apgar after delivery, and have a baby who needed breathing assistance at birth. However the researchers of the study were unable to eliminate selection bias by restricting the study to women who didn't have other medical issues that could be a contributing factor to these findings.
The researchers hope their research will help inform the clinical decisions of doctors who encounter pregnant women. They advise that while a discussion of risks and benefits is important but the decision to stop or maintain treatment should be based on the woman's needs and the severity of her ADHD symptoms.
The authors caution that, even though stopping the medication is an option to consider, it is not recommended because of the high incidence of depression and other mental disorders among women who are pregnant or who have recently given birth. Further, the research suggests that women who decide to stop taking their medication are more likely to experience a difficult time adapting to life without them following the baby's arrival.
Nursing
The responsibilities of a new mother can be overwhelming. Women with ADHD who have to deal with their symptoms while attending doctor appointments and preparing for the arrival of their child and adjusting to new household routines are often faced with a number of difficulties. This is why many women elect to continue taking their ADHD medications throughout pregnancy.
The risk to a breastfeeding infant is not too high since the majority of stimulant medication is absorbed through breast milk at a low level. However, medication for adult add of exposure to medication by the newborn may differ based on dosage, how often it is administered, and at what time the medication is administered. In addition, individual medications enter the infant's system differently through the gastrointestinal tract as well as breast milk and the impact of this on a newborn infant is not well known.
Due to the absence of research, some physicians may recommend stopping stimulant medications during a woman's pregnancy. It is a difficult decision for the mother, who must weigh the advantages of her medication against the risks to the fetus. In the meantime, until more information is available, doctors can inquire about pregnant patients whether they have a background of ADHD or if they intend to take medication during the perinatal period.
Numerous studies have proven that women can continue taking their ADHD medication in a safe manner during pregnancy and while breast-feeding. In response, a growing number of patients are choosing to do this. They have concluded, in consultation with their physicians that the benefits of keeping their current medication outweigh possible risks.
It is essential for women with ADHD who are considering breastfeeding to seek out a specialist psychiatrist's guidance prior to becoming pregnant. They should discuss their medication with their physician and discuss the advantages and disadvantages of continuing treatment, including non-pharmacological strategies. Psychoeducation is also necessary to help pregnant women with ADHD understand the symptoms and underlying disorder. They should also be educated about treatment options and build strategies for coping. This should be an approach that is multidisciplinary, including the GP doctors, obstetricians and psychiatrists. Pregnancy counselling should include discussion of a management plan for both mother and child, as well as monitoring for signs of deterioration, and when necessary, making adjustments to the medication regimen.